From Cancun airport, the cheapest way is to take an ADO bus (airport-Cancun) to downtown, then from downtown take a cab or uber.
From Cancun, the easiest way is to follow Bonampak Avenue to the north, then this same street becomes a road called PROLONGACIÓN BONAMPAK. A drive through the mangroves, leaving Puerto Juarez and Punta Sam on your right, past the Hotel Villas del Palmar until you reach a traffic circle with the road to Playa Mujeres.
Follow that paved road all the way with the golf course on your right until you reach another traffic circle where a new paved road begins. Follow this road past the Costa Mujeres traffic circle, continue straight until it becomes a dirt road.
Drive 3 km on the dirt road until you find an IKARUS sign on your left and a large blue post on your right. Turn left and follow the sand road to the end, and you've arrived! We are on the lagoon side